Picks for week 17.
Last week of the regular season. None of these picks take into account teams with a clinched playoff spot, and will be resting some of their players for the playoffs.
| Game | APR | SRS | ITP |
| Grand Rapids Rampage @ New Orleans VooDoo | VooDoo ρ=1.1305 | VooDoo δ= 8.3 | VooDoo |
| Columbus Destroyers @ Cleveland Gladiators | Gladiators ρ=1.2114 | Gladiators δ= 7.8 | Gladiators |
| Los Angeles Avengers @ Tampa Bay Storm | Storm ρ=1.1788 | Storm δ=10.1 | Storm |
| Kansas City Brigade @ Colorado Crush | Crush ρ=1.0316 | Crush δ= 3.5 | Crush |
| Utah Blaze @ Arizona Rattlers | Rattlers ρ=1.0277 | Blaze δ= 0.5 | Rattlers |
| Georgia Force @ San Jose SaberCats | Force ρ=1.0225 | Force δ= 2.5 | SaberCats |
| Philadelphia Soul @ New York Dragons | Soul ρ=1.0652 | Soul δ= 8.7 | Soul |
| Dallas Desperados @ Chicago Rush | Desperados ρ=1.0714 | Rush δ= 1.9 | Desperados |
